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Mad Cow Disease is the common name for Bovine Spongiform Encephalopathy (BSE). BSE is a transmissible, neurodegenerative, deadly brain disease of cattle. The disease usually takes 2 to 8 years to show signs of infection from the time an animal first becomes infected.
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But it is often fatal within weeks to months of its onset. Most cases in Great Britain occurred in dairy cows between 3 and 6 years of age. Currently, there is neither known treatment nor vaccine to prevent BSE.
Infected cows are observed to have mood changes. They usually become more aggressive or nervous. They also may have difficulty in rising, trouble standing or walking, and show decreased milk production. Despite normal eating habit and appetite, loss of body weight is usually seen. Their condition deteriorates until eventually they either die or are destroyed.
BSE in cattle was first reported in November 1986 in the United Kingdom. Since then, over 178,000 cattle have been diagnosed with BSE in Great Britain. The peak of the epidemic happened in January 1993 when approximately 1,000 new cases were reported per week.
The exact origin of BSE remains a mystery. However, some scientists believe that cattle may have become infected by eating contaminated feed from scrapie-infected sheep meat and bone. Outbreaks occurred when these BSE infected cattle were killed and fed to calves.
The pathology of BSE is still not completely understood. But it is thought that a modified form of protein known as prion is the culprit. This protein may turn infectious and accumulate in the affected animal’s brain or spinal cord leading to damage and degeneration of these tissues and functions. Under a microscope, BSE lesions appear to be sponge-like in character. Unfortunately, these abnormal prions are highly stable and very resilient. They can not be destroyed by common food disinfection measures such as freezing, drying, or heat.
Even though BSE is a form of infectious disease affecting cattle only, its variant, Creutzfeldt-Jacob Disease (vCJD) has been found in humans. vCJD is believed to be caused by eating contaminated beef products from BSE-affected cattle. So far, 155 human cases have been confirmed worldwide with vCJD as the probable cause. But there is only one reported case of vCJD in the United States, in which a young woman who contracted the disease while residing in the UK and developed symptoms after moving to the U.S.
As BSE has not been known to spread through milk, milk and milk products are considered to be safe. Additionally, safety guidelines have been established and enforced through health organizations such as the World Health Organization (WHO) and the United States Department of Agriculture (USDA). Under these guidelines, the use of ruminant tissues in ruminant feed is prohibited.
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