adapalene
(a-DAP-a-leen)

Brand Name:  Differin

Why is this medicine prescribed?

This medicine is a retinoid-like compound used to treat mild to
moderate acne.  
     

How should I take this medicine?

Adapalene is applied to the skin as a cream, gel, or pledget.  It is for
external use only.  Do not take by mouth. Follow the directions on the
prescription label.  Make sure the skin is clean and dry by washing the
affected area with a mild soap and gently dry.   Apply just enough to
cover the affected area.  Rub in gently.  
     

What if I missed a dose?

If you miss a dose, skip that dose and continue with your regular
schedule.  Do not use extra doses, or use for a longer period of time
than directed by your prescriber.
     

What are the possible side effects?  

Side effects that may go away during the treatment include redness,
itching, dryness, peeling, stinging, or a feeling of warmth.  If they
continue or are bothersome, check with your doctor.  CHECK WITH
YOUR DOCTOR AS SOON AS POSSIBLE if you experience blistering,
crusting, swelling, or excessive redness or peeling of your skin.


What drugs may interact with this medicine?

Drug interactions with adapalene are not expected.
     

What special instructions or precautions should I follow while using
this medicine?

Do not get this medicine in your eyes or on the inside of your nose or
mouth.  Your acne may get worse during the first treatment period.  This
is expected.  Do not stop using the medicine during this time as it may
take 2 to 12 weeks before you see the full benefit.  Do not wash your
face more than 2 to 3 times a day unless told by your prescriber.  While
you are using this medicine, you may use cosmetics but wash your face
thoroughly after using cosmetics and before applying this medicine.  

Adapalene may increase sensitivity of the skin to the sun or UV light.  
Avoid exposure to the sun, sunlamps, or tanning booths until you know
how you react to this medicine.  Use a sunscreen SPF 15 or higher if
you must be outside.

If you plan on becoming pregnant, discuss with your doctor the benefits
and risks of using this medicine during pregnancy.  It is unknown if this
drug is excreted in breast milk.  If you are or will be breast-feeding while
using this medicine, discuss the risks and benefits with your doctor or
pharmacist.


Where can I store this medicine?        

Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 to 77
degrees F) away from heat and light.  

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